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ME 615

Microfluidics

Fluids behave differently when channels shrink to the size of a human hair: viscosity dominates over inertia, surface effects and electric double layers start steering the flow, and intuition built from macroscale pipes stops working. The course builds the physics and modeling tools to handle that regime — Stokes flow, electrokinetics, capillarity, two-phase transport — and asks you to apply them through homework sets, simulations of phenomena like electro-osmosis and Joule heating, and a term project that culminates in a presentation. It is a graduate elective that assumes solid fluid mechanics and transport background, and it is the entry point into lab-on-a-chip and BioMEMS research, where the same equations underpin diagnostic chips, droplet assays, and particle-sorting devices.

Credit3ECTS5FacultyFaculty of EngineeringBölümMechanical Engineering

Önerilen kaynaklar 5 kitap

📖
Önerilen
Micro and Nanoscale Fluid Mechanics
Brian J. Kirby
📖
Önerilen
Theoretical Microfluidics
Henrik Bruus
📖
Önerilen
Electrokinetics in Micro?uidics
Dongqing Li
📖
Önerilen
Micro?ows and Nano?ows: Fundamentals and Simulations
G. Karniadakis, A. Beskok
N. Aluru
📖
Önerilen
Basic Transport Phenomena in Biomedical Engineering
Ronald L. Fournier

Haftalık müfredat 14 hafta

Hafta 1
Lab-on-a-chip Technology; Modeling Fluid Flow at Microscale
Hafta 2
Modeling Fluid Flow at Microscale
Hafta 3
Basics of Internal Fluid Flow; The Electric Double Layer
Hafta 4
Basic Electrokinetic Phenomena in Microfluidics: Electro-osmosis, Electrophoresis, Streaming Potential
Hafta 5
Electroviscous Effects
Hafta 6
Electro-osmotic Flows; Simulation of Electroviscous Effects and Electro-osmotic Flow
Hafta 7
Electromechanics of Particles: Electrophoresis, Dielectrophoresis
Hafta 8
AC-Electrokinetics; Effect of Joule Heating on Electrokinetic Transport
Hafta 9
Effect of Joule Heating on Electrokinetic Transport; Simulation of Electrokinetic Transport with Joule Heating
Hafta 10
Miscellaneous Concepts in Microfludics: Optofluidics, Magnetophoresis, Acoustofluidics
Hafta 11
Fabrication Techniques for Microfluidics
Hafta 12
Elementary Convective Heat Transfer in Channels; Microscale Effects on Convective Heat Transfer
Hafta 13
Convective Heat Transfer in Microchannels
Hafta 14
Two-phase flow in Microchannels

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⚠️ FZ engelleyen şartlar

Course Learning Outcomes: Course Learning Outcome Assessment Understand applications of microsystems Homework #1 Able to analyze capillary and wetting phenomena Midterm Exam Homework #2 Able to analyze flow dynamics of droplet-based transport Midterm Exam Homework #3 Able to solve low Reynolds number flow systems Midterm Exam Term project Homework #4 Able to analyze Stokes flow Midterm Exam Term project Homework #5 Able to understand and model mixing and diffusion at microscale Midterm Exam Home

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Emine Yegan Oyman, Barbaros Çetin