Fundamental concepts and experimental techniques in molecular biology, statistical mechanics of polymers, review of solid and fluid mechanics. Mechanics of cellular polymers. Polymer networks and cytoskeleton. The role of stress in cytoskeleton dynamics as related to cell growth, spreading, motility and adhesion. Cellular mechanotransduction. Current research topics in cellular biomechanics.
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Course Learning Outcomes: Course Learning Outcome Assessment Reviewing how the main results of Mechanical Engineering can be applied to the study of cells and subcellular components. Quiz Midterm Final Describing different experimental techniques used in the cellular biomechanics research. Quiz Midterm Final Describing main components of cellular structure and their elastic properties. Quiz Midterm Final Describing fundamental mechanical processes in cellular motiliy, division and adhesion. Quiz
Overview of recent research topics on Cellular Mechanics. Introduction to Statistical Mechanics Statistical Mechanics Fundamentals of Cellular Biology. Brief review of Solid Mechanics. Polymer Networks. Review of Fluid Mechanics. Additional Information: Elements of a Research Proposal. Cell Mechanics in the Laboratory. Recent Experimental Techniques. Polymer Networks and Cytoskeleton. Biomembranes Electrostatics Across Cell Membrane Dynamic Filaments Cellular Mechanotransduction. The Whole Cell Course Review ECTS - Workload Table: Activities Number Hours Workload Project (including preparation and presentation if applicable) 1 20 20 Preparation for Quiz 2 3 6 Presentation (including preparation) 1 10 10 Course hours 14 3 42 Report (including preparation and presentation if applicable) 1 10 10 Preparation for Midterm exam 1 15 15 Final exam 1 2 2 Preparation for Final exam 1 20 20 Individual or group work 14 2 28 Midterm exam 1 2 2 Total Workload: 155 Total Workload / 30: 155 / 30 5.17 ECTS Credits of the Course: 5 Type of Course: Lecture