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CHEM 571

Special Topics in Organic Chemistry I

A graduate seminar that uses pharmaceutical chemistry — specifically photodynamic therapy and singlet-oxygen chemistry — as a lens for reading the current organic chemistry literature critically. You'll spend most of the term digging into recent papers on photosensitizers, molecular logic gates, and activatable therapeutic agents, then presenting and defending your analysis in front of the class rather than grinding through problem sets. It assumes you already have solid synthetic organic foundations and pushes you toward the kind of literature fluency and retrosynthetic thinking you'll need for thesis research at the interface of organic, photophysical, and medicinal chemistry.

Credit3ECTS5FacultyFaculty of ScienceBölümChemistry

Önerilen kaynaklar 2 kitap

📕
Zorunlu
Pharmaceutical Chemistry Vol 1 Drug Design and Action 2nd Ed
JMC Rosa
2024 · de Gruyter
📕
Zorunlu
LIFE SAVING DRUGS The Elusive Magic Bullet
JOHN MANN
2004 · RSC

Haftalık müfredat 14 hafta

Hafta 1
Basic concepts in pharmaceutical chemistry
Hafta 2
Basic concepts in pharmaceutical chemistry
Hafta 3
Basic concepts in pharmaceutical chemistry
Hafta 4
Light absorption, emission, Jablonski diagram revisited
Hafta 5
Photosensitization, Resonance energy transfer
Hafta 6
Photoinduced electron transfer, photoinduced charge transfer, luminescent probes
Hafta 7
Molecular Logic gates, Classes of common photosensitizer dyes
Hafta 8
Activatable photosensitizers
Hafta 9
Molecular logic and PDT
Hafta 10
Towards Autonomous therapeutic agents
Hafta 11
Controlling singlet oxygen
Hafta 12
Endoperoxides as chemical sources of singlet oxygen
Hafta 13
Selected examples of the potential of targeted singlet oxygen
Hafta 14
Selected examples of the potential of targeted singlet oxygen-II

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⚠️ FZ engelleyen şartlar

Course Learning Outcomes: Course Learning Outcome Assessment Able to apply independent and analytical thinking skills Final:Essay/written Midterm:Essay/written Oral presentation Able to communicate effectively to describe the scientific concepts Final:Essay/written Midterm:Essay/written Oral presentation Able to recognise the current trends in organic synthesis Final:Essay/written Midterm:Essay/written Oral presentation Able to plan and evaluate multi-step organic reaction sequences using basic

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Geçmişte ders veren (2 kişi)
Engin Umut Akkaya, Dönüş Tuncel