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MBG 466

Introduction to Cellular and Molecular Biology of the Brain

This course treats the brain as a molecular and cellular system, working from the biophysics of a single neuron's membrane up through synaptic transmission, signaling cascades, and the circuits that produce movement, sensation, and emotion. You'll move between lectures, primary-literature presentations, and case studies on neurological and psychiatric disorders, so the work is as much about reading and explaining mechanisms as it is about memorizing them. It sits at the point where the cell biology, biochemistry, and genetics you've already taken converge on a real organ, and it's the natural entry point before any deeper neuroscience or neuropharmacology elective.

Credit3ECTS5FacultyFaculty of ScienceBölümMolecular Biology and Genetics

Önerilen kaynaklar 3 kitap

📕
Zorunlu
From molecules to networks. An Introduction to Cellular and Molecular Neuroscience
John H. Byrne, Ruth Heidelberger
M. Neal Waxham · 3rd edition. 2014
📖
Önerilen
Neuroscience: Exploring the Brain
Mark F. Bear, Barry Connors
Mike Paradiso · 4th Ed. 2020
📖
Önerilen
Fundamental Neuroscience
Larry Squire
Fourth Edition · Elsevier

Haftalık müfredat 14 hafta

Hafta 1
Introduction to neurobiology
Hafta 2
Structure and cellular elements of the nervous system
Hafta 3
Electrical properties of the cell membrane
Hafta 4
Synaptic transmission (presynaptic mechanisms)
Hafta 5
Synaptic transmission (postsynaptic mechanisms, ion channels and receptors)
Hafta 6
Secondary messenger systems
Hafta 7
Amino acid neuromediators
Hafta 8
Amine and peptide neuromediators
Hafta 9
Gene regulation, learning and memory
Hafta 10
Networks underlying brain functions (movement, sensation, emotions etc.)
Hafta 11
Basic mechanisms and pharmacology of neurological disorders
Hafta 12
Basic mechanisms of and pharmacology psychiatric disorders
Hafta 13
Presentations and case studies
Hafta 14
Presentations and case studies

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⚠️ FZ engelleyen şartlar

Students should have (i) at least 70% attendance, (ii) 10 out of 100 from the mid-term exam and (iii) 10 out of 100 from the presentation.

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