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MSN 522

Synthetic Biology

Synthetic biology treats the cell as something you can engineer: take the molecular parts list that evolution gave us — promoters, transcription factors, RNA elements — and wire them into circuits that do what you want, from toggle switches to repressilators to logic gates. You'll move between Uri Alon's network-motif math (autoregulation, feedback, optimal circuit design) and the bench itself, with three lab modules plus a project where you design, build, and write up a device. Coming in with molecular biology and some quantitative comfort helps; what you build here is the foundation for systems biology, biosensing, and the metabolic-engineering work downstream.

Credit3ECTS5BölümMaterials Science and Nanotechnology

Önerilen kaynaklar 3 kitap

📖
Önerilen
An Introduction to Systems Biology
Uri Alon
2010 · Chapman Hall
📖
Önerilen
Synthetic Biology - A Primer
Baldwin, Bayer
Dickinson · Ellis
📖
Önerilen
Regenesis
George Church, Ed Regis
2014 · Basic Books

Haftalık müfredat 14 hafta

Hafta 1
Synthetic Biology : Making the Cell from Molecules
Hafta 2
Fundamentals of Synthetic Biology : Biological Systems Engineering
Hafta 3
Fundamentals of Synthetic Biology : Methods and Techniques
Hafta 4
Principles of Eukaryotic&Prokaryotic Gene expression, Advanced Techniques in Genetic Engineering-2
Hafta 5
Transcription Networks : Basic Concepts
Hafta 6
Autoregulation and Feedback Loops in Biological Systems
Hafta 7
Optimal Gene Circuit Design
Hafta 8
Biological Device Designs Principles : Genetic Circuitry in Biological Systems and Synthetic Genetic Circuitry Design
Hafta 9
RNA Devices in Biosystems and Synthetic RNA Devices
Hafta 10
Synthetic Biology Devices : Optogenetic Systems, Repressilators, Genetic Logic Gates, Riboswitches, Genetic Toggle Switch
Hafta 11
Synthetic Biology Laboratory -1
Hafta 12
Synthetic Biology Laboratory -2
Hafta 13
Synthetic Biology Laboratory -3
Hafta 14
Laboratory Reports and Presentations

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Geçmiş GPA dağılımı 10 dönem · ort. 3.57

DönemCourse CPA
2023-2024 Fall 3.76 1 sec · 7 öğr
2022-2023 Fall 3.73 1 sec · 12 öğr
2021-2022 Fall 3.62 1 sec · 12 öğr
2020-2021 Fall 3.58 1 sec · 12 öğr
2019-2020 Fall 3.58 1 sec · 10 öğr
2018-2019 Fall 3.55 1 sec · 13 öğr
2017-2018 Fall 3.13 1 sec · 8 öğr
2016-2017 Fall 3.34 1 sec · 15 öğr
2015-2016 Fall 3.67 1 sec · 14 öğr
2014-2015 Fall 3.74 1 sec · 10 öğr

Aggregate course GPA — Bilkent STARS'tan public data. Hoca-bazlı per-section detayı için STARS evaluation report →. Öğrenci anket cevapları KVKK kapsamında defter'de tutulmaz.

⚠️ FZ engelleyen şartlar

1. taking midterm exam 2. submission of the term paper 3. not missing any of the Quiz exams

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