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MBG 222

Fundamentals of Molecular Genetics

This is where you stop thinking about genetics as Mendelian crosses and start thinking about it as molecular machinery: how DNA actually gets copied, repaired, recombined, transcribed, and translated at the level of the enzymes and regulatory logic that run the show. Most of the work happens through close reading of Genes XII chapters paired with two midterms, plus presentations, reports, and group exercises where you defend interpretations of real research findings rather than just memorize pathways. It sits on top of introductory genetics and biochemistry and feeds directly into everything downstream in the MBG curriculum — gene expression, biotech, and lab courses all assume you can already reason about replicons, operons, and translation mechanics fluently.

Credit3ECTS5FacultyFaculty of ScienceBölümMolecular Biology and Genetics

Değerlendirme 40% — 2 adım

20%
20%
Midterm Midterm I, Midterm II 40%

Önerilen kaynaklar 4 kitap

📕
Zorunlu
Genes XII
Krebs, Goldstein
Kilpatrick · 2018
📖
Önerilen
Genetics Analysis & Principles
Robert J Brooker, 6th or newer
📖
Önerilen
Molecular Cell Biology
Harvey Lodish Arnold Berk S Lawrence Zipursky Paul Matsudaira David Baltimore and James Darnell, 4th or newer
https://www.ncbi.nlm.nih.gov/books/NBK21475/
📖
Önerilen
Gene Cloning and DNA Analysis: An Introduction
T. A. Brown, 8th

Haftalık müfredat 14 hafta

Hafta 1
Introduction to the course
Hafta 2
Replication Is Connected to the Cell Cycle (Chapter 9 )
Hafta 3
The Replicon: Initiation of Replication (Chapter 10)
Hafta 4
DNA Replication (Chapter 11)
Hafta 5
Extrachromosomal Replicons (Chapter 12)
Hafta 6
Midterm I
Hafta 7
Homologous and Site-Specific Recombination (Chapter 13)
Hafta 8
Repair Systems (Chapter 14)
Hafta 9
Prokaryotic Transcription (Chapter 17)
Hafta 10
Midterm II
Hafta 11
Translation (Chapter 22)
Hafta 12
Using the Genetic Code (Chapter 23)
Hafta 13
The Operon (Chapter 24)
Hafta 14
Phage Strategies (Chapter 25)

🤖 GenAI politikası

Please refer to the Guidelines for the Use of Generative Artificial Intelligence (GenAI) Tools at Bilkent (https://w3.bilkent.edu.tr/bilkent/generative-artificial-intelligence-genai-guideline/).

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Geçmiş GPA dağılımı 16 dönem · ort. 2.52

DönemCourse CPA
2024-2025 Spring 1.73 1 sec · 12 öğr
2023-2024 Spring 1.86 1 sec · 10 öğr
2022-2023 Spring 2.58 1 sec · 29 öğr
2021-2022 Spring 0.90 1 sec · 5 öğr
2020-2021 Spring 2.20 1 sec · 12 öğr
2019-2020 Spring 2.10 1 sec · 11 öğr
2018-2019 Spring 2.20 1 sec · 10 öğr
2017-2018 Spring 2.08 1 sec · 7 öğr
2016-2017 Spring 2.14 1 sec · 10 öğr
2015-2016 Spring 2.55 1 sec · 14 öğr

Aggregate course GPA — Bilkent STARS'tan public data. Hoca-bazlı per-section detayı için STARS evaluation report →. Öğrenci anket cevapları KVKK kapsamında defter'de tutulmaz.

⚠️ FZ engelleyen şartlar

60% attendance & above zero grade per midterm exam are necessary to avoid "FZ" letter grade.

Hocalar 1 bu dönem · 4 geçmiş

Bu dönem (2025-2026 Spring) · 1 section
Pınar Önal
Geçmişte ders veren (4 kişi)
Murat Alper Cevher, Serkan Belkaya, Ayça Arslan Ergül, Uygar Halis Tazebay